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因为近来中东萨斯病,还要说说“毛”。

楼主:wannian 时间:2015-06-02 16:36:40 点击:716 回复:14
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  本版,我已经两次提到纤毛了:谈小旋风的雾霾;读张维波的经络研究。现在,适逢中东萨斯病(Mers),纤毛问题再次显露,说一说有意义。
  因为有关消息知识到处传播,我仅补充该病对纤毛的“交集”。中东萨斯病病毒入侵气管粘膜,引起呼吸困难。据研究,受累气管粘膜,仅限于无纤毛区域或节段。气管纤毛摆动,本有推卸病变物质的功能。如果纤毛摆动不良,紊乱,则气管易生病变。更何况,如果这个纤毛缺如!看看南韩两位病殁者,俱为老龄。老龄,纤毛调节功能下降,尚能摆否?
  无毛也罢,有毛无力也罢,这些都是病毒内陷的一个可能的原因。研究强调无毛,我看不如把有毛无力也算上,这也是个思路。
  据此推理,又毛且孔武有力的气管,不易患病了?是的。但是,这类气管强悍的咳嗽祛痰,竟然又多出传染性能。真真气人!
  如果将皮肤表面即表皮多毛,看作纤毛弱生指标,则,多毛尤其是多胸毛者,应为萨斯病易感者。反过来推理,表皮毛发不重之亚洲人种,可能不是易感人群。
  小结,对于中东萨斯病而言。气管纤毛弱的易感,强的易传。统统隔离,千真万确。
楼主wannian 时间:2015-06-02 16:40:01
  参见
  MERS-CoV besitzt eine hohe Affinit?t zu Bronchialepithelzellen, die keine Zilien tragen. Das Virus umgeht die Mechanismen der angeborenen Immunit?t und hemmt die Interferonproduktion in diesen Zellen. Dieser Tropismus ist für einen Atemwegserreger ungew?hnlich, da die meisten Viren die in den Atemwegen h?ufiger vorkommenden, zilientragenden Epithelzellen befallen.
作者 :春江沐雨 时间:2015-06-02 21:36:17
  看过,不懂。
楼主wannian 时间:2015-06-04 14:41:21
  谢谢!
  这里有很多信息,可参读:
  The first “index” patient, a 68-year-old employee of an agricultural products company, returned home on May 4 via Qatar after visiting Bahrain, the United Arab Emirates and Saudi Arabia.

  He developed a fever and cough, both symptoms of MERS, on May 11 and sought care at three clinics. But doctors did not suspect MERS because he did not tell them about his Middle East trip. A doctor and a nurse from those clinics later tested positive for the virus.

  It was not until May 18 that a doctor at a larger hospital asked the government authorities to test the man for the virus. Two days later, he was declared the country’s first MERS case. Twenty-seven other cases have since been traced to that hospital.

  One of them, a 44-year-old man who visited his father there, flew to China on May 26 via Hong Kong, although he had been advised by doctors to stay home. The penalty for ignoring such advice is a fine of up to 3 million won, or $2,700. He tested positive in China and was quarantined there last week.

  Another patient, a 58-year-old woman, was infected through contact with the first patient but was released after treatment for asthma. The health authorities did not trace her to another hospital until Sunday. She died of MERS on Monday.

  “We apologize for the inappropriate initial responses,” Moon Hyung-pyo, the minister of health and welfare, said Tuesday at a news conference. “We were too relaxed.”
楼主wannian 时间:2015-06-04 14:44:15
  接上文:
  In yet another case, a 40-year-old man who stayed in the same hospital ward as the first patient to get treatment for pneumonia was released after his condition appeared to have improved. Officials traced him to another hospital on Sunday. The next day, two patients who shared a room with him there tested positive. They were the first tertiary, or third-generation, infections reported. Until then, the government had said that such third-generation cases were unlikely.

  The Education Ministry said it was advising schools to consider temporarily closing if they feared a mass infection among students. But during a news briefing on Wednesday, Kwon Jun-wook, a senior Health Ministry official, called the closing of schools “medically wrong.” Kim Woo-joo, head of the Korean Society of Infectious Diseases, also opposed the closing of schools, calling it too drastic a precaution.

  注意这些传染,显然以没有口罩屏障为条件。
楼主wannian 时间:2015-06-04 21:33:41
  南韩方面传来第三位死亡病例消息,死者82岁,沾染病毒以前就多病缠身。

  韩国人民几乎全都带上了口罩。除了口腔吸入,眼结膜感染带病毒小水泡,也是一径。

  Mers病死亡率40%。现在,韩国死了三个,按这个比例,该有多少病人呢?答案为7个。
  而韩国目前报道病毒阳性者36人。韩国有关部门需要努力,增加救活,拉拉统计的后腿。
楼主wannian 时间:2015-06-05 15:38:00
  一目了然
  红的表明死亡例
  
楼主wannian 时间:2015-06-10 14:06:51
  这两天思来想去:纤毛的功能是在细胞间传递水。纤毛的调节蛋白对细胞间“水质”应该是敏感的。根据花粉病哮喘的观察,如果细胞间液酸碱度变化,则纤毛调节紊乱。因为酸碱变动使调节蛋白失去对“水”的感觉。

  萨斯病死者多为老人,老人一般黏膜多干燥。所以,酸碱变化如何不要紧,只要弄出“干”的效果,就可以。

  湿润气管黏膜,刺激纤毛调节蛋白,这是治疗要点。
楼主wannian 时间:2015-06-16 13:44:42
  世卫今天开会。疫情未见止歇。所以,按我想法,眼感染途径不可忽视。
  忽然想起眼美容。

  眼膜干燥,似乎更容易受到病毒飞沫侵袭。
楼主wannian 时间:2015-06-19 15:38:17
  http://www.nature.com/emi/journal/v4/n4/full/emi201526a.html

  厦门大学研制,抗原检测。这个成果在这次韩国爆发前就已搞出。
  检测样品取自口鼻黏膜。按我想法,经由眼传染,这个容易漏诊。

  世卫表扬韩国为高度专业的预防措施。
楼主wannian 时间:2015-06-20 14:46:38
  今天是端午。为端午申遗且成功的韩国,今年一定是“莫谈端午”的气氛。户服艾以盈要兮,谓幽兰其不可佩,好晦气!
楼主wannian 时间:2015-06-25 13:19:23
  想:单峰驼上呼吸道纤毛摆动单方而向内,或者说这是个倾向。这么说可以触通诸多疑点,包括肾功能衰竭。

  纤毛摆动障碍,要点捋出。
楼主wannian 时间:2015-06-25 13:53:10
  具体到人,这样分析:
  鼻粘膜干湿倾向:一般来说,干性的,不太有花粉过敏,因为花粉是干性的,不为水包裹的;湿性的,容易有花粉过敏。
  骆驼的鼻粘膜是干性的,其粘膜可以从空气中摄入水分。
  打嚏喷,表示湿性粘膜。因为纤毛外摆。
  总结:干性鼻粘膜,纤毛摆动向内。
  由于骆驼感染冠状病毒,推理干性粘膜容易感染病毒----病毒有水分子包裹的情况下。眼结膜干燥同理。
  推理,花粉尤其是树花粉过敏者,不容易作新冠状病毒重病者。但,这一类人很容易作中间传染者。
  南韩病重死人多是老人。老人多粘膜干燥。
  抱歉都是些未加整理的想法。
楼主wannian 时间:2015-07-03 13:26:07
  饱受肆虐,终于缓解。韩国好惨。

  美国某公司搞出了抗体,小鼠试验初见有效。因为小鼠一般不感染中东萨斯,所以研制颇为棘手。南韩病人中有勇者,可以尝试以鼠抗体作被动免疫治疗。
作者 :俺也披马甲蝗 时间:2017-04-13 10:01:11
  你那意思是说把雾霾的颗粒搞成煤矿水泥一样再戴个口罩就没问题了?那你这个研究结果赶快申请专利吧!国家赶快发展煤矿水泥厂就好了。科学家就是科学家!

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